Relationship between arginase activity and renal function in sera of patients with the two types of diabetes mellitus

Abstract

Biochemical study was carried out to evaluate the activity of organs in sera of patients with two types of diabetes mellitus-DM ( 1 and 68 of type II ) as compared with healthy individuals as a control group. Biochemical parameters in the sera of groups which include: serum glucose,renal function-urea, creatinine and uric acid, the results indicate that the level of serum glucose,urea and creatinine significantly increased in the sera of patients with type I and II of diabetes militias as compared with a control group with no significant change in sera of patients with the two types of DM for uric acid as compared with the control group.The result showed significant change between control and patients with DM for serum arginase activity, and between the two types of DM, in which the mean±SD were (2.702±0.673)μmol/L/min in sera of type I of DM and (2.384±0.577) μmol/L/min for type II, the results indicate that the level of the enzyme significantly slightly higher in type I than type II. The correlation between the arginase activity and other biochemical parameters in patients with the two types of DM and control were studied, from the results we conclude that the activity of arginase was the effect by the disease (two types of DM), and the effect was slightly higher by type two of DM.