Drug Design, Development and Therapy (Mar 2022)
Platelet Rich Plasma and Its Use in Hair Regrowth: A Review
Abstract
Anon Paichitrojjana,1 Anand Paichitrojjana2 1School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, Bangkok, Thailand; 2Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Anon Paichitrojjana, School of Anti-Aging and Regenerative Medicine, Mae Fah Luang University, 36/87-88 PS Tower 25Fl, Asoke Road, Sukhumvit 21, Klong Toey Nua, Wattana, Bangkok, 10110, Thailand, Tel +66 81-9343050, Email [email protected]: Platelet rich plasma (PRP) was described as a small volume of plasma containing higher concentrations of platelets than those found in peripheral blood and initially used as a transfusion product for treatment of thrombocytopenia. To date, it was discovered that there are several growth factors and cytokines that can accelerate wound healing and tissue regeneration, leading to a wider range of applications in the medical field, such as in sport medicine, regenerative medicine, and aesthetic medicine. Several studies have shown that PRP can be used effectively for treatment of hair loss. Although it has been widely used, the exact mechanism of action of PRP is still not fully elucidated. In this article, we aim to review and update current information on the definition, classification, mechanism of action, clinical efficacy in hair regrowth, and adverse events of PRP.Keywords: platelet rich plasma, androgenetic alopecia, female pattern hair loss, alopecia areata, cicatricial alopecia, hair transplantation
