THE ROLE OF ENDOTOXIN IN DEVELOPMENT OF SUPPURATIVE-SEPTIC DISEASES AND METHODS OF ENDOTOXIN LEVEL DETERMINATION IN BLOOD

Abstract

The severity and duration of suppurative inflammation of different locations is directly dependent on the level of lipopolysaccharides (endotoxin) in blood. Detection of this value and its dynamics during therapy enables determination of the treatment tactics and its correction. Examination of endotoxin level in biological fluids is a necessary diagnostic component in the therapeutic-and-prophylactic institutions. Today, highly sensitive methods such as LAL-test in different modifications and MAP-test (method of activated particles) are widely practised.

Keywords

• endotoxin
• lipopolysaccharide
• suppurative inflammation
• endotoxemia
• gram-negative microorganisms