Cytokines response during a month of detraining in trained and overweight men

Abstract

Background: Training-induced physiological adaptations reduced during detraining, but researches are limited about the comparison of the effects of detraining after different types of training. Thus, the aim of this study was to compare the effects of one month detraining on cytokines concentrations in aerobic- (AT) and resistance trained (RT) and overweight men. Materials and Methods: In this quasi-experimental study, 19 trained men (25-38 years) were assigned to RT (n=10) and AT (n=9) groups, based on the types of training. The groups were matched by the physical activity level, age and body mass index. The subjects avoided to perform any exercises for a month. All subjects were taken blood samples to measure serum levels of interleukin (IL)-10, IL-17A, and IL-20 before and after the detraining period. Results: After 4 weeks of detraining, body fat percentage and waist circumference increased significantly in the AT and RT groups, while the maximal oxygen consumption in these groups was significantly decreased (for all variables, P0.05). The concentration of IL-17A (P=0.049) showed a significant increase only in the RT group; however, no significant differences were noted for IL-10 and IL-20 concentrations in response to the detraining period in both groups (both, P0.05). Conclusion: It seems that the negative effects caused by one month of detraining are more prominent in the RT group (increase in IL-17A).

Keywords

• Interleukin-17
• Maximal oxygen consumption
• Cessation of training
• Active men