Data on common carotid artery occlusion inducing focalized stroke lesions after Pertussis toxin injection
Veronika Leiss,
Roland P. Piekorz,
Salvador Castaneda Vega,
Christoph Jacoby,
Ulrich Flögel,
Katja Pexa,
Jürgen Schrader,
Bernd J. Pichler,
Sandra Beer-Hammer,
Bernd Nürnberg
Affiliations
Veronika Leiss
Department of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany
Roland P. Piekorz
Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Salvador Castaneda Vega
Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Department of Nuclear Medicine and Clinical Molecular Imaging, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany
Christoph Jacoby
Institute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Ulrich Flögel
Institute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Katja Pexa
Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Jürgen Schrader
Institute of Molecular Cardiology, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany
Bernd J. Pichler
Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University, Tübingen, Germany
Sandra Beer-Hammer
Department of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany; Cluster of Excellence iFIT (EXC 2180) “Image-Guided and Functionally Instructed Tumor Therapies”, Eberhard Karls University, Tübingen, Germany; Corresponding author.
Bernd Nürnberg
Department of Pharmacology, Experimental Therapy and Toxicology, and Interfaculty Center for Pharmacogenomics and Drug Research, Eberhard Karls University Tübingen and University Clinic, Tübingen, Germany
This article contains raw and processed data related to research published by Vega et al. (2022). This complementary dataset provides further insight into the experimental validation of a single common carotid artery occlusion (CCAO) model upon pretreatment with pertussis toxin (PTX). We present data showing the extent of different PTX concentrations on neurological severity measured by Bederson score following CCAO. In addition, data indicate a protective effect of isoflurane on cerebral infarction and neurological deficits, as well as the consequences of PTX pretreatment on reperfusion after occlusion using time-of-flight magnetic resonance angiography. With these data, we aim to provide detailed experimental settings of this newly described model.
