Pharmaceutics (Jun 2021)

Design of the Prototype of Contact Drawing Device for Potential Individual Therapeutic Fiber Formation Purposes

  • István Sebe,
  • István Kovács,
  • Romána Zelkó

DOI
https://doi.org/10.3390/pharmaceutics13060875
Journal volume & issue
Vol. 13, no. 6
p. 875

Abstract

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Pharmaceutical compounding enables the preparation of unlicensed medicine to meet specific patient needs that do not have a licensed medicine available on the market. It must be performed in the best possible circumstance by certified pharmacists using validated standard operating procedures to obtain the highest quality medicinal product. The various spinning techniques provide drug delivery systems easily adapted to individual patient’s needs among the emerging technologies. The primary purpose of the present work was to introduce the prototype of a contact drawing device for the compounding of drug delivery systems for individual in-patient needs. The preliminary experiments resulted in oriented fibers of micrometer diameter range. The device can be placed in controlled conditions and could provide drug-loaded fibrous sheets for further treatments assuring the individual patient’s medicine need of the required quality.

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