Biosynthesis of chromium oxide nanoparticles by Momordica charantia leaf extract: Characterization and their Antibacterial Activities

Abstract

For the synthesis of chromium oxide nanoparticles (Cr2O3 NPs), environmentally safe ingredients like plant extract offer many advantages in terms of eco-friendliness and suitability for pharmacological applications. Momordica charantia leaf extract was employed in this investigation as a reducing agent to create Cr2O3 NPs. Characterization of the Cr2O3 NPs was made by X-ray diffraction (XRD), UV–Visible Spectroscopy, Fourier transform infrared spectroscopy (FTIR), Field Emission Electron Microscopy (FESEM) and Energy dispersive X – ray analysis (EDAX). The formation of Cr2O3 NPs was clearly demonstrated by the appearance of two absorption peaks at 271 nm and 371 nm in the UV- visible spectrum. The bands at 562 cm −1 and 888 cm −1 in the FTIR of Cr2O3 NPs are attributable to Cr-O vibration and Cr=O vibration, respectively. Highly crystalline Cr2O3 NPs were confirmed by XRD patterns, and FESEM revealed that they were often irregular in shape and fewer than 100 nm in size. In Momordica charantia leaf extract, phenolic chemicals were primarily responsible of stabilizing​ and reducing Cr2O3 NPs. The biosynthesized Cr2O3 NPs showed significant antibacterial activity against Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Vibrio cholerae.

Keywords

• Green synthesis
• Chromium oxide nanoparticles
• Momordica charantia leaf extract
• Characterization
• Antimicrobial Activity