Cancer Reports (Dec 2023)

Renal vein thrombosis due to metastatic germ cell tumor, report of a case with a very rare clinical scenario

  • Hamidreza Ghorbani,
  • Ali Emadi Torghabeh,
  • Mahdi Farzadnia,
  • Alireza Golshan,
  • Parisa Rabiei

DOI
https://doi.org/10.1002/cnr2.1910
Journal volume & issue
Vol. 6, no. 12
pp. n/a – n/a

Abstract

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Abstract Background Renal metastasis is a rare manifestation of germ cell tumors. Extension of malignant lesions into the renal vein can complicate the scenario. Case This report presents a 35‐year‐old man with primary stage IS NSGCT. Fourteen months after radical orchiectomy he presented with metastasis in the lung, kidney, and para‐aortic lymph nodes. He received multiple lines of salvage treatments including chemotherapy and surgery. Intraoperative exploration during radical nephrectomy and retroperitoneal lymphadenectomy revealed intra‐renal vein involvement with a prominent teratomatous component. Conclusion Defining the exact extent of malignant lesions, especially endovascular lesions, is very important to clarify how advanced the malignant lesions are. The surgeons must be aware of the risk factors that predict vascular involvement, and therefore, providing intraoperative access to vascular surgery procedures when needed.

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