Peer Community Journal (Nov 2021)

Pipeline to detect the positional and directional relationship between transposable elements and adjacent genes in host genome

  • Meguerditchian, Caroline,
  • Ergun, Ayse,
  • Decroocq, Veronique,
  • Lefebvre, Marie,
  • Bui, Quynh-Trang

DOI
https://doi.org/10.24072/pcjournal.57
Journal volume & issue
Vol. 1

Abstract

Read online

Understanding the relationship between transposable elements (TEs) and their closest positional genes in the host genome is a key point to explore their potential role in genome evolution. Transposable elements can regulate and affect gene expression not only because of their mobility within the genome but also because of their transcriptional activity. A comprehensive knowledge of structural organization between transposable elements and neighboring genes is important to study TE functional role in gene regulation. We implemented a pipeline which is capable to reveal the positional and directional relationship between TEs and adjacent gene distribution in the host genome. Our tool is freely available here: https://github.com/marieBvr/TEs_genes_relationship_pipeline