Hematology, Transfusion and Cell Therapy (Oct 2023)
A PEDIATRIC CHRONIC EOSINOPHILIC LEUKEMIA CASE SUCCESFULLY TREATED WITH STEM CELL TRANSPLANTATION AFTER TRANSFORMATION TO ACUTE LYMPHOBLASTIC LEUKEMIA
Abstract
Chronic eosinophilic leukemia (CEL) is an extremely severe and rare disease in childhood with a very poor prognosis, frequently transforms to acute leukemia in a few years, and once transformed median survival time is only 2 months. Here we present a 9-year-old boy with CEL, transformed to acute lymphoblastic leukemia 17 months after diagnosis and successfully treated with chemotherapy and unrelated stem cell transplantation, he is still in remission after 7 years without any chronic morbidities.