IEEE Access (Jan 2021)

Intelligent Deep Brain Stimulation Systems: A General Review

  • Sikander Khan,
  • Farida Khan,
  • Qurat Ul Ain Sikander,
  • Muhammad Mansoor Alam,
  • Mazliham Mohd Su'Ud

DOI
https://doi.org/10.1109/ACCESS.2021.3105457
Journal volume & issue
Vol. 9
pp. 136929 – 136943

Abstract

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Brain Stimulation is now becoming the preferred approach where pharmacological treatment is ineffective in neurological conditions such as Parkinson’s Disease (PD), Tourette Syndrome, Addiction disorder, Depression, and Anxiety. The brain can be stimulated by electrical current, light, and sound energy, invasively or non-invasively. The article comprises of pathophysiology in Parkinson’s, current pharmacological modalities used for the treatment (along with limitations), and deep brain stimulation as the last resort. The article also provides a comprehensive analysis of intelligent Deep Brain Stimulation methods (procedure, architecture, and type) from the studies and research conducted in the last five years. In the end, research gaps and associated challenges are discussed.

Keywords