Objective: A clinical case of successful medical rehabilitation of a patient with monostotic fibrous osteodisplasy of mandible is presented. After resection of the branch and body of the left mandible with disarticulation in the temporomandibular joint, the defect was replaced by free revascularized fibula flap. The missing joint process was restored with a titanium condylar endoprosthesis, and fixed to the proximal part of autotransplant using special screws.