Nature Communications (Dec 2019)
Wireless, battery-free, fully implantable multimodal and multisite pacemakers for applications in small animal models
- Philipp Gutruf,
- Rose T. Yin,
- K. Benjamin Lee,
- Jokubas Ausra,
- Jaclyn A. Brennan,
- Yun Qiao,
- Zhaoqian Xie,
- Roberto Peralta,
- Olivia Talarico,
- Alejandro Murillo,
- Sheena W. Chen,
- John P. Leshock,
- Chad R. Haney,
- Emily A. Waters,
- Changxing Zhang,
- Haiwen Luan,
- Yonggang Huang,
- Gregory Trachiotis,
- Igor R. Efimov,
- John A. Rogers
Affiliations
- Philipp Gutruf
- Department of Biomedical Engineering, University of Arizona
- Rose T. Yin
- Department of Biomedical Engineering, The George Washington University
- K. Benjamin Lee
- Department of Biomedical Engineering, The George Washington University
- Jokubas Ausra
- Department of Biomedical Engineering, University of Arizona
- Jaclyn A. Brennan
- Department of Biomedical Engineering, The George Washington University
- Yun Qiao
- Department of Biomedical Engineering, The George Washington University
- Zhaoqian Xie
- Department of Engineering Mechanics, Dalian University of Technology
- Roberto Peralta
- Department of Aerospace and Mechanical Engineering, University of Arizona
- Olivia Talarico
- Department of Biomedical Engineering, University of Arizona
- Alejandro Murillo
- Department of Biomedical Engineering, The George Washington University
- Sheena W. Chen
- Department of Biomedical Engineering, The George Washington University
- John P. Leshock
- Department of Biomedical Engineering, McCormick School of Engineering and Applied Science, Northwestern University
- Chad R. Haney
- Center for Advanced Molecular Imaging, Radiology, and Biomedical Engineering, Northwestern University
- Emily A. Waters
- Center for Advanced Molecular Imaging, Northwestern University
- Changxing Zhang
- AML, Department of Engineering Mechanics, Interdisciplinary Research Center for Flexible Electronics Technology, Tsinghua University
- Haiwen Luan
- Department of Civil and Environmental Engineering, Mechanical Engineering, and Materials Science and Engineering, Northwestern University
- Yonggang Huang
- Department of Civil and Environmental Engineering, Mechanical Engineering, and Materials Science and Engineering, Northwestern University
- Gregory Trachiotis
- DC Veterans Affairs Medical Center, The George Washington University
- Igor R. Efimov
- Department of Biomedical Engineering, The George Washington University
- John A. Rogers
- Departments of Materials Science and Engineering, Biomedical Engineering, Neurological Surgery, Chemistry, Mechanical Engineering, Electrical Engineering and Computer Science, Simpson Querrey Institute and Feinberg Medical School, Center for Bio-Integrated Electronics, Northwestern University
- DOI
- https://doi.org/10.1038/s41467-019-13637-w
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 10
Abstract
Pacing tools that support small animals and can serve as models for pathogenesis of cardiovascular diseases are currently not available. Here, the authors report a miniaturized wireless battery-free implantable multimodal and multisite pacemaker that provides unlimited stimulation to test subjects.