Journal of Family Medicine and Primary Care (Jan 2022)

Management of pregnant female with Haemophilia-A: A case report

  • Indu Lata,
  • Amrit Gupta,
  • Deepti Saxena,
  • Ashmina Rekhi,
  • Sandeep Sahu

DOI
https://doi.org/10.4103/jfmpc.jfmpc_2351_21
Journal volume & issue
Vol. 11, no. 9
pp. 5683 – 5685

Abstract

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Haemophilia-A is a rare, X-linked recessive inherited disease affects males and females are carrier results in prolonged bleeding after minor injuries, procedures or surgery. Spontaneous or recurrent bleeding may occur in deep muscles, joints but intracranial haemorrhage can be dangerous. Women with a family history of bleeding disorder, personal history of bleeding (menorrhagia, mucous membrane, postoperative bleeding and PPH) or a prolonged activated partial thromboplastin time (aPTT) should be screened for haemophilia by measuring coagulation factor VIII level during hospital visits for these reason or antenatal care (ANC). Female heterozygote carriers may have variable presentation of bleeding due to reduced levels of clotting FVIII and may experience excessive bleeding due to gynaecologic issues, during spontaneous abortion, medical termination of pregnancy or invasive prenatal diagnostic techniques in first trimester of pregnancy, antepartum and postpartum haemorrhage in later part of gestation and after delivery.

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