Development of a Wearable Sweat Sensor Chip Based on Surface-Enhanced Raman Spectroscopy
Cristiano D’Andrea,
Martina Banchelli,
Chiara Amicucci,
Panagis Polykretis,
Filippo Micheletti,
Marella de Angelis,
Yurim Han,
Heebo Ha,
Byungil Hwang,
Paolo Matteini
Affiliations
Cristiano D’Andrea
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Martina Banchelli
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Chiara Amicucci
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Panagis Polykretis
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Filippo Micheletti
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Marella de Angelis
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
Yurim Han
School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea
Heebo Ha
School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea
Byungil Hwang
School of Integrative Engineering, Chung-Ang University, Seoul 06974, Republic of Korea
Paolo Matteini
Institute of Applied Physics “Nello Carrara” (IFAC), Italian National Research Council (CNR), Via Madonna del Piano 10, Sesto Fiorentino, 50019 Florence, Italy
A wearable sweat sensor chip based on surface-enhanced Raman spectroscopy is developed. The plasmonic core of the chip, obtained by depositing silver nanowires on a PTFE porous membrane, permits the direct and label-free detection of urea and lactate at physiological concentration in combination with the evaluation of sweat pH in the range between 4 and 9.