mSystems (Jun 2021)

Molecular Mechanisms of the Toll-Like Receptor, STING, MAVS, Inflammasome, and Interferon Pathways

  • Nathan P. Manes,
  • Aleksandra Nita-Lazar

DOI
https://doi.org/10.1128/mSystems.00336-21
Journal volume & issue
Vol. 6, no. 3

Abstract

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Pattern recognition receptors (PRRs) form the front line of defense against pathogens. Many of the molecular mechanisms that facilitate PRR signaling have been characterized in detail, which is critical for the development of accurate PRR pathway models at the molecular interaction level.