Педиатрическая фармакология (Oct 2012)

N-TERMINAL PRO-BRAIN NATRIURETIC PEPTIDE IN DIAGNOSTICS OF NON-COMPACTED MYOCARDIUM IN CHILDREN

  • E. N. Arkhipova,
  • I. V. Sil’nova,
  • E. N. Basargina,
  • I. V. Dvoryakovskii,
  • A. B. Sugak,
  • N. A. Mayanskii,
  • M. K. Umarova

DOI
https://doi.org/10.15690/pf.v9i5.457
Journal volume & issue
Vol. 9, no. 5
pp. 65 – 69

Abstract

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Non-compacted myocardium is a rare congenital cardiomyopathy. Due to the lack of uniform criteria, diagnostics of this condition is complicated presently, which results in over-diagnosing. N-terminal pro-brain natriuretic peptide (NT-proBNP) is a marker of chronic cardiac insufficiency (CCI) in children. The results of the study of NT-proBNP in non-compacted myocardium diagnostics are represented in this article. It was established, that serum NT-proBNP levels were higher in children with non-compacted myocardium than in children with CCI and without this disorder (р < 0,01). The received data can be useful in clinical practice.

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