The Role of <i>Brassica</i> Bioactives on Human Health: Are We Studying It the Right Way?
Sarai Quirante-Moya,
Paula García-Ibañez,
Francisco Quirante-Moya,
Débora Villaño,
Diego A. Moreno
Affiliations
Sarai Quirante-Moya
Centro de Salud Callosa del Segura, Paseo Enrique Tierno Galvan, 19, E-03360 Alicante, Spain
Paula García-Ibañez
CEBAS-CSIC, Department of Plant Nutrition. Aquaporins Group, Campus Universitario de Espinardo-25, E-30100 Murcia, Spain
Francisco Quirante-Moya
CEBAS-CSIC, Department of Plant Nutrition. Aquaporins Group, Campus Universitario de Espinardo-25, E-30100 Murcia, Spain
Débora Villaño
Faculty of Health Sciences, Department of Pharmacy, Universidad Católica de San Antonio de Murcia (UCAM), Campus de los Jerónimos, E-30107 Guadalupe, Murcia, Spain
Diego A. Moreno
CEBAS-CSIC, Department of Food Science and Technology, Phytochemistry and Healthy Foods Lab, Research Group on Quality, Safety and Bioactivity of Plant Foods, Campus de Espinardo-25, E-30100 Espinardo, Murcia, Spain
Brassica vegetables and their components, the glucosinolates, have been suggested as good candidates as dietary coadjutants to improve health in non-communicable diseases (NCDs). Different preclinical and clinical studies have been performed in the last decade; however, some concerns have been posed on the lack of established and standardized protocols. The different concentration of bioactive compounds used, time of intervention or sample size, and the lack of blinding are some factors that may influence the studies’ outcomes. This review aims to analyze the critical points of the studies performed with Brassica-related biomolecules and propose some bases for future trials in order to avoid biases.
