Nature Communications (Mar 2021)
Mechanisms and targets of Fcγ-receptor mediated immunity to malaria sporozoites
- Gaoqian Feng,
- Bruce D. Wines,
- Liriye Kurtovic,
- Jo-Anne Chan,
- Philippe Boeuf,
- Vanessa Mollard,
- Anton Cozijnsen,
- Damien R. Drew,
- Rob J. Center,
- Daniel L. Marshall,
- Sandra Chishimba,
- Geoffrey I. McFadden,
- Arlene E. Dent,
- Kiprotich Chelimo,
- Michelle J. Boyle,
- James W. Kazura,
- P. Mark Hogarth,
- James G. Beeson
Affiliations
- Gaoqian Feng
- Burnet Institute for Medical Research and Public Health
- Bruce D. Wines
- Burnet Institute for Medical Research and Public Health
- Liriye Kurtovic
- Burnet Institute for Medical Research and Public Health
- Jo-Anne Chan
- Burnet Institute for Medical Research and Public Health
- Philippe Boeuf
- Burnet Institute for Medical Research and Public Health
- Vanessa Mollard
- School of BioSciences, The University of Melbourne
- Anton Cozijnsen
- School of BioSciences, The University of Melbourne
- Damien R. Drew
- Burnet Institute for Medical Research and Public Health
- Rob J. Center
- Burnet Institute for Medical Research and Public Health
- Daniel L. Marshall
- Burnet Institute for Medical Research and Public Health
- Sandra Chishimba
- Burnet Institute for Medical Research and Public Health
- Geoffrey I. McFadden
- School of BioSciences, The University of Melbourne
- Arlene E. Dent
- Centre for Global Health and Diseases, Case Western Reserve University
- Kiprotich Chelimo
- Department of Biomedical Science and Technology, Maseno University
- Michelle J. Boyle
- Burnet Institute for Medical Research and Public Health
- James W. Kazura
- Centre for Global Health and Diseases, Case Western Reserve University
- P. Mark Hogarth
- Burnet Institute for Medical Research and Public Health
- James G. Beeson
- Burnet Institute for Medical Research and Public Health
- DOI
- https://doi.org/10.1038/s41467-021-21998-4
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 16
Abstract
Antibodies plays critical roles in the adaptive immune response to infectious agents including malaria. Here the authors defined antibody interactions with -Fcγ-receptors expressed on immune cells with sporozoites of Plasmodium falciparum, and identified specific target epitopes of antibodies.
