Does electrical stimulation improve healing in acute minor burn injury, as measured by bioimpedance spectroscopy? A single center, randomized, controlled trial
Dale O. Edwick,
Dana A. Hince,
Jeremy M. Rawlins,
Fiona M. Wood,
Dale W. Edgar
Affiliations
Dale O. Edwick
State Adult Burns Unit, Fiona Stanley Hospital, South Metropolitan Health Service, Murdoch, Western Australia, Australia; Fiona Wood Foundation, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; School of Physiotherapy, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Burn Injury Research Node, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Corresponding author at: State Adult Burns Unit, Fiona Stanley Hospital, South Metropolitan Health Service, CDO15, 102-118 Murdoch Drive, Murdoch, Western Australia 6150, Australia.
Dana A. Hince
Institute for Health Research, The University of Notre Dame Australia, Fremantle, Western Australia, Australia
Jeremy M. Rawlins
State Adult Burns Unit, Fiona Stanley Hospital, South Metropolitan Health Service, Murdoch, Western Australia, Australia; Department of Plastic and Maxillofacial Reconstruction, Royal Perth Hospital, East Metropolitan Health Service, Perth, Western Australia, Australia
Fiona M. Wood
State Adult Burns Unit, Fiona Stanley Hospital, South Metropolitan Health Service, Murdoch, Western Australia, Australia; Fiona Wood Foundation, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; Burn Injury Research Unit, The University of Western Australia, Crawley, Western Australia, Australia
Dale W. Edgar
State Adult Burns Unit, Fiona Stanley Hospital, South Metropolitan Health Service, Murdoch, Western Australia, Australia; Fiona Wood Foundation, Fiona Stanley Hospital, Murdoch, Western Australia, Australia; Burn Injury Research Node, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Institute for Health Research, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Burn Injury Research Unit, The University of Western Australia, Crawley, Western Australia, Australia
Background: Electrical stimulation (ES) has been shown to improve wound healing in chronic wounds. Recent studies in burn injured populations have demonstrated that ES improved edema and healing using short duration stimulation. This study utilized a low energy long duration ES using a portable device. The aim was to determine how this mode of stimulation influences the acute burn wound, as measured using bioimpedance spectroscopy (BIS). Our group has previously validated the use of BIS for measuring edema changes with wound healing in burn injured patients. Methods: This study is a within patient control, randomized study of 30 patients (24 male) presenting with burns to multiple limbs. One affected limb was randomized to receive ES and routine dressings. The other wound received routine care only. Minor burn wounds were stimulated for 10–14 days for more than 20 h/day. Serial localized BIS resistance and phase angle raw data measures were used to monitor edema and wound responses with treatment. Results: Multi-level mixed effects regression analyses demonstrated phase angle at 50 kHz increased at a faster rate in the stimulated wound. Stimulated wounds exhibited an increased rate of edema reduction as measured by extracellular tissue impedance. Conclusion: ES was confirmed to be an easily applied adjunct therapy to improve the rate of edema reduction in acute minor burn injury, and positively influences phase angle measures in the acute burn wound.
