mSystems (Jun 2021)

Spinal Cord Injury Changes the Structure and Functional Potential of Gut Bacterial and Viral Communities

  • Jingjie Du,
  • Ahmed A. Zayed,
  • Kristina A. Kigerl,
  • Kylie Zane,
  • Matthew B. Sullivan,
  • Phillip G. Popovich

DOI
https://doi.org/10.1128/mSystems.01356-20
Journal volume & issue
Vol. 6, no. 3

Abstract

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To our knowledge, this is the first article to apply metagenomics to characterize changes in gut microbial population dynamics caused by a clinically relevant model of central nervous system (CNS) trauma. It also utilizes the most current approaches in genome-resolved metagenomics and viromics to maximize the biological inferences that can be made from these data.