DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders

• Melissa Lim,
• Thang Do Cong,
• Lauren M. Orr,
• Ethan S. Toriki,
• Andrew C. Kile,
• James W. Papatzimas,
• Elijah Lee,
• Yihan Lin,
• Daniel K. Nomura

Affiliations

Melissa Lim

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Thang Do Cong

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Lauren M. Orr

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Ethan S. Toriki

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Andrew C. Kile

Novartis-Berkeley Translational Chemical Biology Institute, Berkeley, California, United States

James W. Papatzimas

Novartis-Berkeley Translational Chemical Biology Institute, Berkeley, California, United States

Elijah Lee

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Yihan Lin

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States

Daniel K. Nomura

Department of Chemistry, University of California, Berkeley, Berkeley, California, United States