Nature Communications (Feb 2017)
Recurrently deregulated lncRNAs in hepatocellular carcinoma
- Yang Yang,
- Lei Chen,
- Jin Gu,
- Hanshuo Zhang,
- Jiapei Yuan,
- Qiuyu Lian,
- Guishuai Lv,
- Siqi Wang,
- Yang Wu,
- Yu-Cheng T. Yang,
- Dongfang Wang,
- Yang Liu,
- Jing Tang,
- Guijuan Luo,
- Yang Li,
- Long Hu,
- Xinbao Sun,
- Dong Wang,
- Mingzhou Guo,
- Qiaoran Xi,
- Jianzhong Xi,
- Hongyang Wang,
- Michael Q. Zhang,
- Zhi John Lu
Affiliations
- Yang Yang
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Lei Chen
- International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University
- Jin Gu
- Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University
- Hanshuo Zhang
- Department of Biomedical Engineering, College of Engineering, Peking University
- Jiapei Yuan
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Qiuyu Lian
- Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University
- Guishuai Lv
- International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University
- Siqi Wang
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Yang Wu
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Yu-Cheng T. Yang
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Dongfang Wang
- Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University
- Yang Liu
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Jing Tang
- Department of Neurosurgery, Wuhan General Hospital of Guangzhou Command
- Guijuan Luo
- International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University
- Yang Li
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Long Hu
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Xinbao Sun
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Dong Wang
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Mingzhou Guo
- Department of Gastroenterology & Hepatology, Chinese PLA General Hospital
- Qiaoran Xi
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Jianzhong Xi
- Department of Biomedical Engineering, College of Engineering, Peking University
- Hongyang Wang
- International Co-operation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Institute, Second Military Medical University
- Michael Q. Zhang
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- Zhi John Lu
- MOE Key Laboratory of Bioinformatics, Center for Synthetic and Systems Biology, Center for Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University
- DOI
- https://doi.org/10.1038/ncomms14421
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 13
Abstract
Long noncoding-RNAs have been linked to hepatocellular carcinoma (HCC) and some can be used as prognostic markers. Here the authors, by analysing RNA-seq in 60 clinical samples from 20 patients, provide a resource of functional lncRNAs and biomarkers associated with HCC tumorigenesis and metastasis.
