Detection of SNP effects on feed conversion ratio in pigs based on entropy approach

Abstract

The objectives of the study were to classify SNPs according to their contribution to the feed conversion ratio and to indicate interactions between the most informative SNPs using entropy analysis. The records of 1296 pigs were included. Two selection criteria for molecular data were applied: call rate 0.95 and minor allele frequency 0.05. After this, 50 951 SNPs were included into the entropy analysis. For each SNP entropy and conditional entropy were estimated. For interaction analyses the most informative SNPs were selected. For each pair of SNPs, the mutual information was assessed. A majority of the loci studied showed relatively small contributions. The most informative SNPs are mainly located on chromosomes: 1, 4, 7, 9 and 14. Whereas important interactions between SNP pairs were detected on chromosomes: 1, 14, 15 and 16. High mutual information was registered for SNPs located nearby.

Keywords

• pigs
• information theory
• feed conversion
• SNP