Journal of Pure and Applied Microbiology (Dec 2022)

Post-COVID-19 Invasive Fungal Sinusitis: A Case Series from Southern India

  • Madhavi S. Hullur,
  • R. Bharathi,
  • R. Bindu Madhavi,
  • Arvind Natarajan,
  • H.S. Brindha,
  • S.M. Azeem Mohiyuddin,
  • R. Kalyani,
  • Anil Kumar Sakalecha,
  • Bukke Ravindra Naik,
  • K.N. Shashidhar

DOI
https://doi.org/10.22207/JPAM.16.4.62
Journal volume & issue
Vol. 16, no. 4
pp. 2961 – 2967

Abstract

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Acute Invasive Fungal Rhinosinusitis (AIFR) is a serious condition with aggressive course and high mortality rates. There is an upsurge in the incidence of invasive fungal rhinosinusitis in post COVID-19 patients. We have come across 20 AIFR cases in post COVID-19 patients. On retrospective exploration of the patient’s records, we found that 30% patients had received steroids and 90% had diabetes. All the patients were managed by administration of IV amphotericin B and local debridement of infected tissues. The mortality rate was as low as 15 %. We conclude that combined approach of Antifungal therapy with debridement of infected tissues improves the prognosis and survival of AIFR patients.

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