Up-regulation of HTR1A reverses stress-induced visceral hypersensitivity through modulating interactions among the anterior cingulate cortex, insular cortex and hippocampus
Xuan Liqian,
Zhou Jingjing,
Yi Lisha,
Xu Shuchang
Affiliations
Xuan Liqian
Digestive Endoscopy Center, Department of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Zhou Jingjing
Digestive Endoscopy Center, Department of Gastroenterology, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China
Yi Lisha
Department of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Xu Shuchang
Department of Gastroenterology, Tongji Hospital, Tongji University School of Medicine, Shanghai, China
Background: This study aimed to explore the effect of 5-HT1A receptors (HTR1A) on activation of the anterior cingulate cortex and simultaneous regulation of neural activity in the insular cortex and hippocampus.
