Promising Approach to Inhibit <em>E.</em> <em>coli</em> FimH Adhesion by <em>C</em>-Linked Mannosides

Abstract

Antagonists of the uropathogenic Escherichia coli type-1 fimbrial adhesin (FimH) are recognized as attractive alternatives for antibiotic therapies and prophylactic strategies against acute and recurrent bacterial infections. [...]

Keywords

• carbohydrate
• D-mannosides
• uropathogenic infections
• <em>E. coli</em>
• lectin
• FimH