Case Reports in Gastroenterology (Jan 2015)

Laparoscopic Resection of Schwannoma of the Ascending Colon

  • Yoshihiko Tashiro,
  • Fumio Matsumoto,
  • Keiko Iwama,
  • Ai Shimazu,
  • Sei Matsumori,
  • Shigeo Nohara,
  • Hiroyoshi Miura,
  • Masahiko Takei,
  • Koji Namekata,
  • Masaru Takase,
  • Motoi Okada,
  • Hidenori Tsumura

DOI
https://doi.org/10.1159/000373882
Journal volume & issue
Vol. 9, no. 1
pp. 15 – 19

Abstract

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Schwannomas of the colon are rare and difficult to diagnose preoperatively. We report a case of schwannoma of the ascending colon that was resected laparoscopically. A 64-year-old woman was referred to our hospital by her local clinic for further evaluation and management of a submucosal tumor of the ascending colon. A definitive preoperative diagnosis could not be reached despite examinations. Gastrointestinal stromal tumor, leiomyoma and lymphoma were the differential diagnoses. We performed a laparoscopic right hemicolectomy with D2 lymph node dissection. Histological findings with hematoxylin-eosin staining revealed spindle-like tumor cells, and immunohistochemical analysis showed that the tumor was positive for S-100 but negative for c-kit, CD34, smooth muscle actin and desmin, with a Ki-67 index of <5%. Thus, the diagnosis in this case was benign schwannoma of the ascending colon.

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