Data on proteomic analysis of milk extracellular vesicles from bovine leukemia virus-infected cattle
Md. Matiur Rahman,
Yassien Badr,
Yuji O. Kamatari,
Yuko Kitamura,
Kaori Shimizu,
Ayaka Okada,
Yasuo Inoshima
Affiliations
Md. Matiur Rahman
The United Graduate School of Veterinary Sciences, Gifu University, Japan; Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Japan; Department of Medicine, Faculty of Veterinary, Animal, and Biomedical Sciences, Sylhet Agricultural University, Sylhet, Bangladesh
Yassien Badr
Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Japan; Department of Animal Medicine, Faculty of Veterinary Medicine, Damanhour University, El-Beheira, Egypt
Yuji O. Kamatari
Division of Instrumental Analysis, Life Science Research Center, Gifu University, Japan
Yuko Kitamura
Gifu Prefectural Chuo Livestock Hygiene Service Center, Japan
Kaori Shimizu
Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Japan
Ayaka Okada
Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Japan; Joint Graduate School of Veterinary Sciences, Gifu University, Japan
Yasuo Inoshima
The United Graduate School of Veterinary Sciences, Gifu University, Japan; Laboratory of Food and Environmental Hygiene, Cooperative Department of Veterinary Medicine, Gifu University, Japan; Education and Research Center for Food Animal Health, Gifu University (GeFAH), Japan; Joint Graduate School of Veterinary Sciences, Gifu University, Japan; Corresponding author at: Gifu University, Japan
Milk extracellular vesicles (EVs) are nanoparticles that contain proteins, mRNAs, microRNAs, DNAs, and lipids that involved in several biological functions. Milk EVs provide proteins that could represent relevant novel biomarkers for monitoring of different diseases such as breast cancer and mastitis in humans and animals, respectively. Bovine leukemia virus (BLV) is an oncogenic virus that causes progressive B-cell lymphosarcoma in cattle. Here, we aimed to identify proteins in milk EVs from BLV-infected cattle compared with those from uninfcetd cattle. Proteomic analysis was performed by using a comprehensive nano liquid chromatography-tandem mass spectrometry (nanoLC-MS/MS) approach. Identified proteins were analyzed by using a proteomic software, Scaffold-Data Independent Acquisition (Scaffold-DIA).
