Nature Communications (Mar 2022)

Dynamics of plasmid-mediated niche invasion, immunity to invasion, and pheromone-inducible conjugation in the murine gastrointestinal tract

  • Helmut Hirt,
  • Kerryl E. Greenwood-Quaintance,
  • Aaron M. T. Barnes,
  • Melissa J. Karau,
  • Lisa M. Till,
  • Elise Palzer,
  • Weihua Guan,
  • Michael S. VanNieuwenhze,
  • Purna C. Kashyap,
  • Robin Patel,
  • Gary M. Dunny

DOI
https://doi.org/10.1038/s41467-022-29028-7
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

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Microbial communities provide protection to their hosts by excluding colonizing pathogens. Here the authors study plasmid transfer and plasmid-mediated effects on host colonization and persistence of Enterococcus faecalis in the intestinal tract of mice.