Papillary thyroid carcinoma presented as a hypercaptant nodule: a case report

Maria Letizia Lai; Jacopo Caschili; Priscilla Baldussu; Alessandra Serra; Lucia Secci; Pietro Giorgio Calò; Clara Gerosa; Daniela Fanni

Endocrine and Metabolic Science (Jun 2024)

Papillary thyroid carcinoma presented as a hypercaptant nodule: a case report

Maria Letizia Lai,
Jacopo Caschili,
Priscilla Baldussu,
Alessandra Serra,
Lucia Secci,
Pietro Giorgio Calò,
Clara Gerosa,
Daniela Fanni

Affiliations

Maria Letizia Lai: Department of Medical Sciences and Public Health, Division of Pathology (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Jacopo Caschili: Department of Medical Sciences and Public Health, Division of Pathology (AOU di Cagliari), University of Cagliari, Cagliari, Italy; Corresponding author.
Priscilla Baldussu: Department of Medical Sciences and Public Health, Division of Pathology (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Alessandra Serra: Department of Medical Sciences and Public Health, Nuclear Medicine Unit (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Lucia Secci: General Surgery (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Pietro Giorgio Calò: General Surgery (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Clara Gerosa: Department of Medical Sciences and Public Health, Division of Pathology (AOU di Cagliari), University of Cagliari, Cagliari, Italy
Daniela Fanni: Department of Medical Sciences and Public Health, Division of Pathology (AOU di Cagliari), University of Cagliari, Cagliari, Italy

Journal volume & issue: Vol. 15
p. 100179

Abstract

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Hot thyroid nodules are mostly benign and rarely show a malignant nature. Here we present the case of a 45-year-old man with a hypercaptant but ultrasound suspicious nodule; he underwent fine needle aspiration (FNA) and subsequent thyroidectomy. Pathology revealed a papillary thyroid carcinoma (PTC) with focal tall cell features, positivity to BRAF V600E and focal hyperspression of p53. A multidisciplinary clinicopathological approach is crucial for the correct diagnosis.

Published in Endocrine and Metabolic Science

ISSN: 2666-3961 (Online)
Publisher: Elsevier
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://www.journals.elsevier.com/endocrine-and-metabolic-science

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