Nature Communications (Mar 2018)
Structures of Teneurin adhesion receptors reveal an ancient fold for cell-cell interaction
Abstract
Teneurins are cell-cell adhesion receptors that evolved through horizontal gene transfer in which a bacterial YD-repeat protein fused to a eukaryotic receptor. Here the authors present crystallographic and cryo-EM structures of two Teneurins, revealing an ancient YD-repeat protein super-fold.