#37. Lactate-GPR81 signaling in acute myeloid leukemia (AML) contributes to bone marrow microenvironment dysfunction, macrophage polarization, and leukemia cell growth

• Celia A. Soto,
• Maggie Lesch,
• Joshua C. Munger,
• Benjamin J. Frisch

Affiliations

Celia A. Soto

Department of Pathology, University of Rochester, Rochester, NY, USA; Wilmot Cancer Institute, University of Rochester, Rochester, NY, USA; Center for Musculoskeletal Research, University of Rochester, Rochester, NY, USA

Maggie Lesch

Department of Microbiology and Immunology, University of Rochester, Rochester, NY, USA

Joshua C. Munger

Department of Biochemistry and Biophysics, University of Rochester, Rochester, NY, USA; Department of Microbiology and Immunology, University of Rochester, Rochester, NY, USA

Benjamin J. Frisch

Department of Pathology, University of Rochester, Rochester, NY, USA; Wilmot Cancer Institute, University of Rochester, Rochester, NY, USA; Center for Musculoskeletal Research, University of Rochester, Rochester, NY, USA; Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA