Вопросы современной педиатрии (Jan 2010)
SAFETY OF TUMOR NECROSIS FACTOR BLOCKERS IN ADULT’S AND CHILDREN’S RHEUMATOLOGIC PRACTICE
Abstract
The article presents the review of a safety of TNF blockers in treatment of rheumatologic diseases in adults and children. Authors give a data on separate, open-labeled, and multicenter double-blinded placebo-controlled studies of tolerance to infliximab, etanercept and adalimumab. The results of studies show high effectiveness and good safety of TNF blockers in adult’s and children’s rheumatologic practice. Key words: children, rheumatoid arthritis, juvenile arthritis, TNF blockers, treatment, safety, infliximab, adalimumab, etanercept.(Voprosy sovremennoi pediatrii — Current Pediatrics. 2010;9(1):82-94)