mSphere of Influence: It’s Not Me, It’s You—How Donor Factors Influence Kidney Transplant Outcomes

Abstract

ABSTRACT Diana V. Pastrana works in the field of DNA tumor virus biology. In this mSphere of Influence article, she reflects on how the two papers “Donor origin of BKV replication after kidney transplantation” (C. Schmitt, L. Raggub, S. Linnenweber-Held, O. Adams, et al., J Clin Virol 59:120–125, 2014, https://doi.org/10.1016/j.jcv.2013.11.009) and “Neutralizing antibody-mediated response and risk of BK virus-associated nephropathy” (M. Solis, A. Velay, R. Porcher, P. Domingo-Calap, et al., J Am Soc Nephrol 29:326–334, 2018, https://doi.org/10.1681/ASN.2017050532) reminded her of the importance of allowing data, and not adherence to dogma, to drive her research.

Keywords

• BKPyV
• BKPyVAN
• BKV
• PVAN
• kidney
• polyomavirus