Frontiers in Neurology (Oct 2023)

SWADESH: a multimodal multi-disease brain imaging and neuropsychological database and data analytics platform

  • Pravat K. Mandal,
  • Pravat K. Mandal,
  • Komal Jindal,
  • Saurav Roy,
  • Yashika Arora,
  • Shallu Sharma,
  • Shallu Joon,
  • Anshika Goel,
  • Zoheb Ahasan,
  • Joseph C. Maroon,
  • Kuldeep Singh,
  • Kanika Sandal,
  • Manjari Tripathi,
  • Pooja Sharma,
  • Avantika Samkaria,
  • Shradha Gaur,
  • Sandhya Shandilya

DOI
https://doi.org/10.3389/fneur.2023.1258116
Journal volume & issue
Vol. 14

Abstract

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Multimodal neuroimaging data of various brain disorders provides valuable information to understand brain function in health and disease. Various neuroimaging-based databases have been developed that mainly consist of volumetric magnetic resonance imaging (MRI) data. We present the comprehensive web-based neuroimaging platform “SWADESH” for hosting multi-disease, multimodal neuroimaging, and neuropsychological data along with analytical pipelines. This novel initiative includes neurochemical and magnetic susceptibility data for healthy and diseased conditions, acquired using MR spectroscopy (MRS) and quantitative susceptibility mapping (QSM) respectively. The SWADESH architecture also provides a neuroimaging database which includes MRI, MRS, functional MRI (fMRI), diffusion weighted imaging (DWI), QSM, neuropsychological data and associated data analysis pipelines. Our final objective is to provide a master database of major brain disease states (neurodegenerative, neuropsychiatric, neurodevelopmental, and others) and to identify characteristic features and biomarkers associated with such disorders.

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