Ocular Manifestations in Patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome in Maha Sarakham

Abstract

HIV-infected patients or AIDS patients could present with various ocular manifestations. This cross-sectional study reports the prevalence and risk factors of ocular manifestations in human immunodeficiency virus (HIV)/ acquired immune deficiency syndrome (AIDS) patients, presented at the HIV/AIDS clinic, Suddhavej Hospital. The study was conducted from July 2017 to June 2018. Data was collected from medical records, patient interview, laboratory investigation and ocular examination. Of the 58 patients with HIV/AIDS, 57 were on antiretroviral therapy. The prevalence of ocular findings was 32.8%, which were dry eye disease (13.79%) followed by retinal microvasculopathy (6.9%), chorioretinal pigmented scar (6.9%), posterior synechiae (3.45%) and herpetic anterior uveitis (1.72%). The rate of ocular manifestation was significantly higher in female patients [AOR=8.4; 95%CI=1.34-52.48; P=0.023]. The subjects in the present study were in younger age group and the level of CD4+ T lymphocytes was quite high. Dry eye disease was the most common ocular manifestation. Female sex was shown to be the risk factor for all of ocular findings.

Keywords

• hiv
• aids
• ocular manifestations
• dry eye