Nature Communications (Mar 2017)

Light-sensing via hydrogen peroxide and a peroxiredoxin

  • Kristofer Bodvard,
  • Ken Peeters,
  • Friederike Roger,
  • Natalie Romanov,
  • Aeid Igbaria,
  • Niek Welkenhuysen,
  • Gaël Palais,
  • Wolfgang Reiter,
  • Michel B. Toledano,
  • Mikael Käll,
  • Mikael Molin

DOI
https://doi.org/10.1038/ncomms14791
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 11

Abstract

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While yeasts lack dedicated photoreceptors, they nonetheless possess metabolic rhythms responsive to light. Here the authors find that light signalling in budding yeast involves the production of H2O2, which in turn regulates protein kinase A through a peroxiredoxin-thioredoxin redox relay.