Current Status of Trachoma Infections and a Discussion on Treatment Approaches: A Comparative Analysis of Azithromycin and Doxycycline

Abstract

Chlamydia trachomatis causes a wide range of diseases, affecting the eyes, genital tract, and other organs, and can also lead to mother-to-child transmission. Genital Chlamydia trachomatis infection specifically refers to a sexually transmitted disease characterized primarily by inflammation of the urogenital tract caused by Chlamydia trachomatis. Here, a brief review of the pathogen biology research on the mechanism of action and pathogenic factors of Chlamydia trachomatis infection is provided. Additionally, through a comparative analysis of the efficacy, resistance data, administration methods, and current clinical application status of azithromycin and doxycycline, this paper reveals the advantages and limitations of the two drugs in the treatment of trachoma, with the aim of providing a basis for further research on Chlamydia trachomatis infections.