PLoS ONE (Jan 2022)

Social cognitive outcomes are associated with improvements in mobility performance following lifestyle intervention in prostate cancer patients undergoing androgen deprivation therapy.

  • Zachary L Chaplow,
  • Alexander R Lucas,
  • Elizabeth Grainger,
  • Christina Simpson,
  • Ciaran M Fairman,
  • Victoria R DeScenza,
  • Jessica Bowman,
  • Steven K Clinton,
  • Brian C Focht

DOI
https://doi.org/10.1371/journal.pone.0263136
Journal volume & issue
Vol. 17, no. 1
p. e0263136

Abstract

Read online

ObjectiveTo compare the effects of an exercise and dietary intervention with those of standard-of-care management upon change in lift and carry performance and mobility-related self-efficacy beliefs and explore associations in prostate cancer patients undergoing androgen deprivation therapy.Methods32 prostate cancer patients (M age = 66.2 years; SD = 7.8) undergoing androgen deprivation therapy were randomly assigned to a 3-month exercise and dietary lifestyle intervention (n = 16) or standard-of-care management (n = 16). Outcome assessments were obtained at baseline, 2- and 3-month follow-up.ResultsThe lifestyle intervention resulted in significantly greater improvements in lift and carry performance (p = 0.01) at 2 Months (d = 1.01; p ConclusionsThe exercise and dietary lifestyle intervention yielded superior improvements in lift and carry performance and mobility-related self-efficacy relative to standard-of-care and key social cognitive outcomes were associated with more favorable mobility performance.