Methylergometrine maleate from synchrotron powder diffraction data

Abstract

The title compound {systematic name: 9,10-didehydro-N-[1-(hydroxymethyl)propyl]-d-lysergamide maleate}, C20H26N3O2+·C4H3O4−, contains a large rigid ergolene group. This group consists of an indole plane connected to a six-membered carbon ring adopting an envelope conformation and N-methyltetrahydropyridine where the methyl group is in an equatorial position. In the crystal, intermolecular N—H...O, O—H...N and O—H...O hydrogen bonds form an extensive three-dimensional hydrogen-bonding network, which holds the cations and anions together.