Malaria Parasite Schizont Egress Antigen-1 Plays an Essential Role in Nuclear Segregation during Schizogony

mBio (Apr 2021)

Affiliations

Abigail J. Perrin: ORCiD; Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom
Claudine Bisson: Department of Biological Sciences, Institute of Structural & Molecular Biology, Birkbeck College, University of London, London, United Kingdom
Peter A. Faull: Mass Spectrometry Proteomics Platform, The Francis Crick Institute, London, United Kingdom
Matthew J. Renshaw: Advanced Light Microscopy, The Francis Crick Institute, London, United Kingdom
Rebecca A. Lees: Department of Biological Sciences, Institute of Structural & Molecular Biology, Birkbeck College, University of London, London, United Kingdom
Roland A. Fleck: Centre for Ultrastructural Imaging, Guy’s Campus, King’s College London, London, United Kingdom
Helen R. Saibil: Department of Biological Sciences, Institute of Structural & Molecular Biology, Birkbeck College, University of London, London, United Kingdom
Ambrosius P. Snijders: Mass Spectrometry Proteomics Platform, The Francis Crick Institute, London, United Kingdom
David A. Baker: ORCiD; Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom
Michael J. Blackman: ORCiD; Malaria Biochemistry Laboratory, The Francis Crick Institute, London, United Kingdom

Abstract

Malaria is a deadly infectious disease. Rationally designed novel therapeutics will be essential for its control and eradication.