PEDIATRIC MDS IN GATA2-DEFICIENCY: ENHANCED HISTONE TRIMETHYLATION AND DEREGULATED APOPTOSIS AS DRIVER?

• Franziska Schreiber,
• Guido Piontek,
• Yuki Schneider-Kimoto,
• Stephan Schwarz-Furlan,
• Rita De Vito,
• Franco Locatelli,
• Carole Gengler,
• Charlotte M. Niemeyer,
• Miriam Erlacher,
• Martina Rudelius

Affiliations

Franziska Schreiber

Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany

Guido Piontek

Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany

Yuki Schneider-Kimoto

Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany

Stephan Schwarz-Furlan

Institute of Pathology, Klinikum Kaufbeuren-Ravensburg, Kaufbeuren, Germany; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany

Rita De Vito

Department of Pathology, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy

Franco Locatelli

Department of Pediatric Hematology and Oncology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy; Department of Life Sciences and Public Health, Catholic University of the Sacred Heart, Rome, Italy

Carole Gengler

Department of Pathology, University Hospital of Lausanne (CHUV), Switzerland

Charlotte M. Niemeyer

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK), Heidelberg and Freiburg, Germany

Miriam Erlacher

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium (DKTK), Heidelberg and Freiburg, Germany

Martina Rudelius

Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany