Nature Communications (Feb 2023)
Topical phage therapy in a mouse model of Cutibacterium acnes-induced acne-like lesions
- Amit Rimon,
- Chani Rakov,
- Vanda Lerer,
- Sivan Sheffer-Levi,
- Sivan Alkalay Oren,
- Tehila Shlomov,
- Lihi Shasha,
- Ruth Lubin,
- Khaled Zubeidat,
- Nora Jaber,
- Musa Mujahed,
- Asaf Wilensky,
- Shunit Coppenhagen-Glazer,
- Vered Molho-Pessach,
- Ronen Hazan
Affiliations
- Amit Rimon
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Chani Rakov
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Vanda Lerer
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Sivan Sheffer-Levi
- Department of Dermatology, Hadassah Medical Center, The Faculty of Medicine, The Hebrew University of Jerusalem
- Sivan Alkalay Oren
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Tehila Shlomov
- Department of Ophthalmology, Hadassah Medical Center, The Faculty of Medicine, The Hebrew University of Jerusalem
- Lihi Shasha
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Ruth Lubin
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Khaled Zubeidat
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Nora Jaber
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Musa Mujahed
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Asaf Wilensky
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Shunit Coppenhagen-Glazer
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- Vered Molho-Pessach
- Department of Dermatology, Hadassah Medical Center, The Faculty of Medicine, The Hebrew University of Jerusalem
- Ronen Hazan
- Institute of Biomedical and Oral Research (IBOR), Faculty of Dental Medicine, The Hebrew University of Jerusalem
- DOI
- https://doi.org/10.1038/s41467-023-36694-8
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 18
Abstract
Bacteriophage therapy is evolving as a promising approach to tackling bacterial infection, even in the case of emerging antibiotic resistance. In this work, authors present the topical application of numerous Cutibacterium acnes phage in an in vivo mouse model of acne vulgaris.
