FREE RADICAL OXIDATION AND CARCINOGENESIS: DEBATABLE ISSUES

Abstract

Free radicals have taken a firm place among the explanatory principles of the onset and development of tumors. Unambiguous ideas about the role of these highly active agents in carcinogenesis have not yet been obtained. The experimental results are contradictory, often the opposite. The field of study of the value of the activity of antioxidant systems based on the results obtained is no less controversial. In this regard, the urgent problem is the need to prescribe antioxidants in oncology. Antitumor effects of antioxidants are being questioned in many works, which brings to the forefront the appropriateness and adequacy of their appointment. The ambiguous role of free radicals in carcinogenesis determines the development of therapeutic strategies based on the precise modulation of oxidative processes.

Keywords

• свободные радикалы
• опухоли
• рак
• противоопухолевые препараты
• антиоксиданты