Педиатрическая фармакология (Apr 2013)
EXPERIENCE OF USING METHOTREXATE IN A PATIENT WITH EARLY OLIGOARTICULAR JUVENILE IDIOPATHIC ARTHRITIS
Abstract
The article describes a case with a severe course of oligoarticular juvenile idiopathic arthritis with the development of contracture and destructive articular alterations. The successful use of methotrexate (15mg/m2 of body surface per week, subcutaneously) in a child with early arthritis (disease duration – less than 2 years) is described: 6 months after the therapy had started, acute inflammatory articular alterations, arthralgiae, morning stiffness terminated; in 12 months the range of motions in the affected joints recovered completely. The inactive disease phase and remission were registered in 6 and 12 months, accordingly. The remission has continued for 12 months.
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