Mathematical Biosciences and Engineering (Mar 2022)
D-optimal design of the additive mixture model with multi-response
Abstract
This paper proposes the D-optimal design for the additive mixture model with two-response, which is linear model with no interaction terms. The optimality was validated by using the general equivalence theorem, and the corresponding weights are found under which additive model satisfies D-optimality. In addition, relevant statistics and graphics are given to illustrate our results.
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