Communications Biology (Jun 2021)

Multiparametric biophysical profiling of red blood cells in malaria infection

  • Shreya S. Deshmukh,
  • Bikash Shakya,
  • Anna Chen,
  • Naside Gozde Durmus,
  • Bryan Greenhouse,
  • Elizabeth S. Egan,
  • Utkan Demirci

DOI
https://doi.org/10.1038/s42003-021-02181-3
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 13

Abstract

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Deshmukh et al. combine microscale magnetic levitation with minute density and magnetic susceptibility differences to enhance biophysical separation of cells. They demonstrate the feasibility of this approach on cells infected with malaria parasites, which simultaneously decrease host cell density and increase its magnetic susceptibility.