Nature Communications (Feb 2022)

An archaellum filament composed of two alternating subunits

  • Lavinia Gambelli,
  • Michail N. Isupov,
  • Rebecca Conners,
  • Mathew McLaren,
  • Annett Bellack,
  • Vicki Gold,
  • Reinhard Rachel,
  • Bertram Daum

DOI
https://doi.org/10.1038/s41467-022-28337-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 11

Abstract

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The archaellum is a molecular machine used by archaea to swim, consisting of an intracellular motor that drives the rotation of an extracellular filament composed of multiple copies of proteins named archaellins. Here, the authors use electron cryo-microscopy to elucidate the structure of an archaellum, and find that the filament is composed of two alternating archaellins.