Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Ace Tatang Hidayat; Kindi Farabi; Ida Nur Farida; Kansy Haikal; Nurlelasari Nurlelasari; Desi Harneti Putri Huspa; Rani Maharani; Unang Supratman; Yoshihito Shiono

doi:10.15408/jkv.v4i1.7065

Jurnal Kimia Valensi (May 2018)

Dammarane-Type Triterpenoids from The Stembark of Aglaia argentea (Meliaceae)

Ace Tatang Hidayat,
Kindi Farabi,
Ida Nur Farida,
Kansy Haikal,
Nurlelasari Nurlelasari,
Desi Harneti Putri Huspa,
Rani Maharani,
Unang Supratman,
Yoshihito Shiono

Affiliations

Ace Tatang Hidayat: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Kindi Farabi: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Ida Nur Farida: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Kansy Haikal: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Nurlelasari Nurlelasari: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Desi Harneti Putri Huspa: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Rani Maharani: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Unang Supratman: Departemen Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Padjadjaran
Yoshihito Shiono: Department of Food, Life, and Environmental Science, Faculty of Agriculture, Yamagata University, Tsuruoka, Yamagata 997-8555, Japan

DOI: https://doi.org/10.15408/jkv.v4i1.7065
Journal volume & issue: Vol. 4, no. 1
pp. 7 – 13

Abstract

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Two dammarane-type triterpenoids, 20S,24S-epoxy-3α,25-dihydroxydammarane (1) and 3α-acetyl-20S,24S-epoxy-3α,25-dihydroxydammarane (2), have been isolated from the stembark of Aglaia argentea. The chemical structure of compounds (1 and 2) were identified by spectroscopic evidences including UV, IR, 1D-NMR, 2D-NMR and MS as well as by comparing with previously reported spectral data. Those compounds were isolated from this plant for first time. Compounds (1 and 2) showed cytotoxic activity against P-388 murine leukemia cells with IC50 values of 23.96 and 8.14 mM, respectively. DOI:http://dx.doi.org/10.15408/jkv.v4i1.7065

Published in Jurnal Kimia Valensi

ISSN: 2460-6065 (Print); 2548-3013 (Online)
Publisher: Syarif Hidayatullah Jakarta State Islamic University
Country of publisher: Indonesia
LCC subjects: Science: Chemistry
Website: http://journal.uinjkt.ac.id/index.php/valensi/

About the journal